Description

8-Bromo-3H-Pyrido[4,3-D]Pyrimidin-4-One is a high-purity, heterocyclic organic compound with the CAS registry number 1256353-15-7, serving as a critical building block in advanced pharmaceutical and agrochemical research. This brominated pyridopyrimidinone derivative is valued for its unique molecular scaffold, which enables the synthesis of novel compounds with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for drug discovery programs and the development of crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used as a precursor in the synthesis of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probe: Serves as a core structure for developing molecular probes to study enzyme function and cellular pathways.
• Material Science Research: Investigated as a precursor for organic electronic materials due to its fused heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and library production.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-3H-Pyrido[4,3-D]Pyrimidin-4-One
CAS No.	1256353-15-7
Molecular Formula	C7H4BrN3O
Molecular Weight	226.03 g/mol
Synonyms	8-Bromo-3H-pyrido[4,3-d]pyrimidin-4-one; 8-Bromo-4H-pyrido[4,3-d]pyrimidin-4-one; 8-Bromo-4-oxo-3,4-dihydropyrido[4,3-d]pyrimidine; 1256353-15-7; 8-Bromopyrido[4,3-d]pyrimidin-4(3H)-one; 8-Bromo-3H-pyrido[4,3-d]pyrimidin-4-ol (tautomer); 8-Bromo-4-hydroxy-3H-pyrido[4,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 8-Bromo-3H-Pyrido[4,3-D]Pyrimidin-4-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP standards for advanced intermediates and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.