Description

2-Borono-6-Trifluoromethylbenzoic Acid is a high-purity, multifunctional organic building block that combines a boronic acid group with a trifluoromethyl-substituted benzoic acid core. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical chemists and agrochemical researchers for constructing novel active compounds, particularly in the development of protease inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially protease inhibitors and boron-containing therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the boronic acid and trifluoromethyl motifs.
• Material Science: Serves as a precursor for advanced organic electronic materials and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The boronic acid functionality enables its use in Suzuki-Miyaura cross-coupling reactions to form biaryl structures.
• Chemical Biology Probes: Utilized in the design of activity-based probes for studying enzyme function and inhibition.
• Ligand Synthesis: Acts as a starting material for creating complex chelating ligands in coordination chemistry.

Basic Information

Product Name	2-Borono-6-Trifluoromethylbenzoic Acid
CAS No.	1256345-62-6
Molecular Formula	C8H6BF3O4
Molecular Weight	233.94 g/mol
Synonyms	2-Boronobenzoic acid, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2-boronobenzoic acid; 2-Carboxy-3-(trifluoromethyl)phenylboronic acid; Benzoic acid, 2-borono-6-(trifluoromethyl)-; (2-Carboxy-3-(trifluoromethyl)phenyl)boronic acid; B-[2-Carboxy-3-(trifluoromethyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Borono-6-Trifluoromethylbenzoic Acid is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure compliance with stringent purity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.