Description

2-(Ethylthio)-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a pivotal method for constructing complex molecules. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing pyridine-containing drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides with enhanced efficacy.
• Material Science: Serves as a precursor for functionalized polymers and liquid crystals with specific electronic properties.
• Chemical Research: Enables the synthesis of complex heterocyclic compounds for academic and industrial discovery programs.
• Ligand & Catalyst Development: Employed in the creation of novel boron-based ligands for catalytic systems.
• Custom Synthesis: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules.

Basic Information

Product Name	2-(Ethylthio)-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid
CAS No.	1256345-55-7
Molecular Formula	C8H9BF3NO2S
Molecular Weight	251.03 g/mol
Synonyms	2-(Ethylthio)-5-(trifluoromethyl)-3-pyridineboronic acid; [2-(Ethylsulfanyl)-5-(trifluoromethyl)pyridin-3-yl]boronic acid; 3-Borono-2-(ethylthio)-5-(trifluoromethyl)pyridine; 2-Ethylthio-5-trifluoromethylpyridine-3-boronic acid; 2-(Ethylmercapto)-5-(trifluoromethyl)-3-pyridylboronic acid; 2-(Ethylsulfanyl)-5-(trifluoromethyl)pyridine-3-boronic acid; 2-(Ethylthio)-5-(trifluoromethyl)-3-pyridinylboronic acid
EINECS	Contact for details

Quality Control

Our production of 2-(Ethylthio)-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your critical synthesis steps. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and residual solvent levels.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Boronic Acid Assay (NMR)	≥ 95.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.