Description

1-(5-Bromo-3-Pyridinyl)Cyclopropanecarboxylic Acid is a high-value, multifunctional organic building block featuring a brominated pyridine core fused with a strained cyclopropane carboxylic acid moiety. This unique molecular architecture makes it a critical intermediate for the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily sought after by research chemists and process development scientists in the agrochemical and pharmaceutical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and cyclopropane motifs.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the research of advanced organic electronic materials and liquid crystals.
• Chemical Biology: Utilized as a probe or linker in bioconjugation chemistry and proteomics research.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-(5-Bromo-3-Pyridinyl)Cyclopropanecarboxylic Acid
CAS No.	1256038-40-0
Molecular Formula	C9H8BrNO2
Molecular Weight	242.07 g/mol
Synonyms	5-Bromo-3-cyclopropanecarbonylpyridine; (5-Bromopyridin-3-yl)cyclopropanecarboxylic acid; 3-Pyridinecarboxylic acid, 5-bromo-, 1-cyclopropyl ester (related); Cyclopropanecarboxylic acid, 1-(5-bromo-3-pyridinyl)-; 1-(5-Bromo-3-pyridyl)cyclopropanecarboxylic acid; BRD-K94211890 (potential screening ID); AI3-63535 (potential registry ID); Building block 1256038-40-0
EINECS	Contact for details

Quality Control

Every batch of 1-(5-Bromo-3-Pyridinyl)Cyclopropanecarboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards typical for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile data is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be kept under inert conditions if long-term storage is required. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.