Description

2-(3-Fluorophenyl)-5-Hydroxy-6-Methoxy-4(1H)-Quinolinone is a high-purity, fluorinated quinolinone derivative, a key building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which is integral to the research and development of novel pharmaceutical agents and bioactive materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new molecular entities with potential therapeutic or functional properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Research: Serves as a core structure for developing new active ingredients for crop protection products, leveraging the fluorophenyl moiety for enhanced bioactivity and stability.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition, receptor binding, and other biochemical pathways due to its specific quinolinone pharmacophore.
• Material Science Precursor: Potential building block for advanced organic electronic materials or metal-organic frameworks (MOFs) where its conjugated system and functional groups can be utilized.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	2-(3-Fluorophenyl)-5-Hydroxy-6-Methoxy-4(1H)-Quinolinone
CAS No.	1256037-41-8
Molecular Formula	C₁₆H₁₂FNO₃
Molecular Weight	285.27 g/mol
Synonyms	5-Hydroxy-6-methoxy-2-(3-fluorophenyl)-4(1H)-quinolinone; 2-(3-Fluorophenyl)-5-hydroxy-6-methoxy-1,4-dihydroquinolin-4-one; 4(1H)-Quinolinone, 2-(3-fluorophenyl)-5-hydroxy-6-methoxy-; 1256037-41-8; 3-Fluoro-5-hydroxy-6-methoxy-2-phenylquinolin-4(1H)-one (related isomer); Fluorophenyl hydroxy methoxy quinolinone
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenyl)-5-Hydroxy-6-Methoxy-4(1H)-Quinolinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.