Description

2-(3-Fluorophenyl)-5,6-Dimethoxyquinolin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate with a distinct quinoline core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic compounds for academic and industrial research.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Biochemical Research: Potential use as a tool compound for probing biological mechanisms and enzyme interactions in vitro.

Basic Information

Product Name	2-(3-Fluorophenyl)-5,6-Dimethoxyquinolin-4(1H)-One
CAS No.	1256037-25-8
Molecular Formula	C₁₇H₁₄FNO₃
Molecular Weight	299.30 g/mol
Synonyms	4(1H)-Quinolinone, 2-(3-fluorophenyl)-5,6-dimethoxy-; 2-(3-Fluorophenyl)-5,6-dimethoxy-1,4-dihydroquinolin-4-one; 5,6-Dimethoxy-2-(3-fluorophenyl)quinolin-4(1H)-one; 2-(3-Fluorophenyl)-5,6-dimethoxy-4-hydroxyquinoline; 4-Hydroxy-5,6-dimethoxy-2-(3-fluorophenyl)quinoline
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenyl)-5,6-Dimethoxyquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.