Description

(R)-1-(4-Chloro-3-Methylphenyl)Ethanamine-Hcl is a high-purity chiral amine hydrochloride salt, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a defined stereocenter essential for creating enantiomerically pure compounds with specific biological activity. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where the specific (R)-configuration can be crucial for efficacy and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the synthesis of complex, high-value specialty chemicals for material science and electronics.
• Academic and Industrial Research: A valuable compound for methodological studies in asymmetric synthesis and medicinal chemistry.

Basic Information

Product Name	(R)-1-(4-Chloro-3-Methylphenyl)Ethanamine Hydrochloride
CAS No.	1255306-36-5
Molecular Formula	C9H13Cl2N
Molecular Weight	206.11 g/mol
Synonyms	(R)-1-(4-Chloro-3-methylphenyl)ethanamine hydrochloride; (R)-1-(4-Chloro-3-methylphenyl)ethylamine HCl; (R)-α-Methyl-4-chloro-m-toluidine hydrochloride; (R)-4-Chloro-3-methyl-α-methylbenzylamine hydrochloride; (R)-1-(4-Chloro-3-methylphenyl)ethan-1-amine hydrochloride; (R)-1-(4-Chloro-3-methylphenyl)ethylammonium chloride
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Chloro-3-Methylphenyl)Ethanamine-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.