Description

7-Chloro-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused triazolopyridine core. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring potent and selective small-molecule modulators. Research and development teams in the global pharmaceutical and agrochemical industries need this precise chemical building block to accelerate their drug discovery and optimization programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the discovery and synthesis of novel pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Biology Probe: Serves as a scaffold for creating tool compounds to study specific biological pathways and protein targets.
• Material Science Research: Investigated as a potential building block for advanced organic electronic materials due to its electron-deficient aromatic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical development pipelines.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Item	Details
Product Name	7-Chloro-3-(Cyclopropylmethyl)-8-(Trifluoromethyl)-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	1254981-30-0
Molecular Formula	C11H9ClF3N3
Molecular Weight	275.66 g/mol
Synonyms	7-Chloro-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine; 7-Chloro-3-(cyclopropylmethyl)-8-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridine; 1254981-30-0; 8-(Trifluoromethyl)-7-chloro-3-(cyclopropylmethyl)[1,2,4]triazolo[4,3-a]pyridine; 3-(Cyclopropylmethyl)-7-chloro-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

Our 7-Chloro-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.