Description

4-Aminoquinoline-6-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an amino group and a nitrile moiety on a quinoline scaffold, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for antimalarial, anticancer, and antiviral research programs.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where the quinoline core contributes to biological activity.
• Ligand Synthesis: Acts as a starting material for creating sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds due to its conjugated system.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis & Scale-up: A key building block for contract research organizations (CROs) and CDMOs offering custom synthesis services from milligram to kilogram scale.

Basic Information

Product Name	4-Aminoquinoline-6-Carbonitrile
CAS No.	1253792-26-5
Molecular Formula	C10H7N3
Molecular Weight	169.18 g/mol
Synonyms	6-Cyano-4-aminoquinoline; 4-Amino-6-cyanoquinoline; Quinoline-6-carbonitrile, 4-amino-; 4-Aminoquinoline-6-carbonitrile; 1253792-26-5; 4-Amino-6-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Aminoquinoline-6-Carbonitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with ISO standards and meets the rigorous demands of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.