Description

Ethyl 4-Hydroxy-2-Oxo-1-(Prop-2-Ynyl)-1,2-Dihydro-1,8-Naphthyridine-3-Carboxylate CAS NO 1253789-55-7 is a high-purity, synthetically valuable naphthyridine derivative. This compound serves as a critical pharmaceutical intermediate and a versatile chemical building block for advanced organic synthesis. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Chemical Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Research: Serves as a starting material for developing new pesticides and herbicides with specific modes of action.
• Organic Synthesis: Utilized in heterocyclic chemistry to construct complex molecular architectures for material science applications.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its specific heterocyclic structure.

Basic Information

Product Name	Ethyl 4-Hydroxy-2-Oxo-1-(Prop-2-Ynyl)-1,2-Dihydro-1,8-Naphthyridine-3-Carboxylate
CAS No.	1253789-55-7
Molecular Formula	C₁₄H₁₂N₂O₄
Molecular Weight	272.26 g/mol
Synonyms	1,8-Naphthyridine-3-carboxylic acid, 1,2-dihydro-4-hydroxy-2-oxo-1-(2-propynyl)-, ethyl ester; Ethyl 1-(2-propynyl)-1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxylate; 1-(Prop-2-yn-1-yl)-1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester; 1253789-55-7; ENP-3-Carboxylate Derivative
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-2-Oxo-1-(Prop-2-Ynyl)-1,2-Dihydro-1,8-Naphthyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.