Description

(S)-4-Benzyl-2-(Quinolin-2-Yl)-4,5-Dihydrooxazole CAS NO 1252576-14-9 is a high-value, chiral oxazoline derivative used as a key intermediate and ligand in advanced chemical synthesis. Its primary value lies in its ability to act as a versatile building block and catalyst component for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and other therapeutic areas requiring high stereochemical purity.
• Asymmetric Catalysis Ligand: Serves as a precursor or direct ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cyclopropanation, and C-H activation, to create chiral centers with high enantioselectivity.
• Agrochemical Synthesis: Used in the research and development of novel, enantiopure pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Material Science Research: Employed in the development of chiral polymers, liquid crystals, and other advanced materials with specific optical or electronic properties.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and for scaling up enantioselective processes from laboratory to pilot plant scale.

Basic Information

Product Name	(S)-4-Benzyl-2-(Quinolin-2-Yl)-4,5-Dihydrooxazole
CAS No.	1252576-14-9
Molecular Formula	C19H16N2O
Molecular Weight	288.35 g/mol
Synonyms	(S)-4-Benzyl-2-(quinolin-2-yl)-4,5-dihydrooxazole; (S)-4-Benzyl-2-(2-quinolyl)-2-oxazoline; (S)-2-(2-Quinolyl)-4-benzyl-2-oxazoline; (S)-4-Benzyl-2-(quinolin-2-yl)-4,5-dihydro-1,3-oxazole; (S)-4-Benzyl-2-(2-quinolinyl)-4,5-dihydrooxazole; (S)-4-Benzyl-2-(quinolin-2-yl)-2-oxazoline; (S)-4-Benzyl-2-(2-quinolyl)-4,5-dihydrooxazole; (S)-4-Phenylmethyl-2-(2-quinolyl)-2-oxazoline
EINECS	Contact for details

Quality Control

Our (S)-4-Benzyl-2-(Quinolin-2-Yl)-4,5-Dihydrooxazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity consistent with research and process chemistry requirements. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.