Description

1-(2-Fluorophenyl)-2-Nitroethanol is a specialized fluorinated nitro alcohol intermediate of significant interest in advanced organic synthesis. Its molecular structure, featuring both a fluorinated aromatic ring and a nitroethanol moiety, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries. It serves as a key precursor in the synthesis of novel active ingredients and fine chemicals requiring specific fluorinated architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated bioisosteres for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom can improve lipophilicity and target binding.
• Fine Chemical Building Block: Employed in organic synthesis for the construction of complex fluorinated molecules, including ligands for catalysis and advanced materials.
• Research & Development: Serves as a critical reagent in academic and industrial R&D labs for methodological studies and exploring new chemical spaces in fluoroorganic chemistry.

Basic Information

Product Name	1-(2-Fluorophenyl)-2-Nitroethanol
CAS No.	1251400-54-0
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	2-Nitro-1-(2-fluorophenyl)ethanol; 1-(2-Fluorophenyl)-2-nitroethan-1-ol; 2-Fluoro-β-nitro-phenethyl alcohol; α-(2-Fluorophenyl)-2-nitroethanol; (2-Fluorophenyl)(nitromethyl)methanol; 2-Nitro-1-(o-fluorophenyl)ethanol; β-Nitro-2-fluorophenethyl alcohol
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Fluorophenyl)-2-Nitroethanol is manufactured and tested under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We are committed to meeting the stringent requirements of research and cGMP-grade material production for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.