Description

3-Bromo-1-(4-Fluorophenyl)-1H-Pyrazole-5-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a brominated pyrazole core with a fluorinated phenyl group and a carboxylic acid handle, enabling precise structural modifications. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly kinase inhibitors and other biologically relevant molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity of the pyrazole-fluorophenyl scaffold.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Potential precursor for the synthesis of specialized ligands in catalysis or functional organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in client-directed synthesis projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	3-Bromo-1-(4-Fluorophenyl)-1H-Pyrazole-5-Carboxylic Acid
CAS No.	1251249-98-5
Molecular Formula	C10H6BrFN2O2
Molecular Weight	285.07 g/mol
Synonyms	3-Bromo-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid; 1-(4-Fluorophenyl)-3-bromo-1H-pyrazole-5-carboxylic acid; 5-Bromo-3-(4-fluorophenyl)-1H-pyrazole-1-carboxylic acid (tautomer form); 1251249-98-5; 3-Bromo-1-(p-fluorophenyl)-1H-pyrazole-5-carboxylic acid; 3-Br-1-(4-F-Ph)-1H-Pyrazole-5-COOH; Pyrazole-5-carboxylic acid, 3-bromo-1-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-1-(4-Fluorophenyl)-1H-Pyrazole-5-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including HPLC, NMR, and MS data, to verify identity and purity. A Certificate of Analysis (COA) detailing lot-specific results is supplied with each shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.