Description

6-Fluoroquinolin-5-Amine is a high-purity fluorinated quinoline derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique fluorine-substituted quinoline core enables precise modulation of biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in antimicrobial, anticancer, and CNS-targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for developing organic electronic materials, ligands for catalysis, and fluorescent dyes or probes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluorine chemistry.
• Scale-up & Process Chemistry: Suitable for optimization and kilogram-scale production under GMP or non-GMP conditions for clinical trial material supply.

Basic Information

Product Name	6-Fluoroquinolin-5-Amine
CAS No.	1251032-63-9
Molecular Formula	C9H7FN2
Molecular Weight	162.16 g/mol
Synonyms	5-Amino-6-fluoroquinoline; 6-Fluoro-5-aminoquinoline; 6-Fluoroquinolin-5-ylamine; Quinoline, 5-amino-6-fluoro-; 1251032-63-9
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinolin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.