Description

cis-tert-Butyl3A-Aminohexahydrocyclopenta[B]Pyrrole-1(2H)-Carboxylate (Wx110094) is a high-purity, advanced pharmaceutical intermediate featuring a complex, conformationally constrained bicyclic structure. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics. It is essential for medicinal chemistry research and process development teams in the pharmaceutical and biotechnology industries seeking to develop new drug candidates with improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up API manufacturing under current Good Manufacturing Practice (cGMP) conditions.
• Protease Inhibitor Synthesis: Potential application in constructing the core structures of protease inhibitors for antiviral and anticancer therapies.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective synthesis to introduce complex molecular architectures.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	cis-tert-Butyl3A-Aminohexahydrocyclopenta[B]Pyrrole-1(2H)-Carboxylate (Wx110094)
CAS No.	1251021-47-2
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	1,2,3,3a,4,5-Hexahydrocyclopenta[b]pyrrole-1-carboxylic acid, 3-amino-, 1,1-dimethylethyl ester, (3aR,1S)-rel-; tert-Butyl (3aR,1S)-3-aminohexahydrocyclopenta[b]pyrrole-1(2H)-carboxylate; cis-1-Boc-3-amino-3-azabicyclo[3.3.0]octane; (1S,3aR)-1-(tert-Butoxycarbonyl)octahydrocyclopenta[b]pyrrol-3-amine; WX-110094; BOC-3-Aminohexahydrocyclopenta[b]pyrrole; (3aR,1S)-tert-Butyl 3-aminohexahydrocyclopenta[b]pyrrole-1(2H)-carboxylate
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl3A-Aminohexahydrocyclopenta[B]Pyrrole-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and chiral purity suitable for advanced pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming compliance with client specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.