Description

4-Chloro-[1,2,4]Triazolo[4,3-A]Quinoxaline-1-Carboxylic Acid Ethyl Ester is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the synthesis of complex triazoloquinoxaline derivatives.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in CNS and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex fused heterocyclic systems in academic and industrial R&D.
• Agrochemical Research: Potential intermediate in the development of new pesticides and herbicides due to its bioactive scaffold.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and specialty dyes.

Basic Information

Product Name	4-Chloro-[1,2,4]Triazolo[4,3-A]Quinoxaline-1-Carboxylic Acid Ethyl Ester
CAS No.	1251017-01-2
Molecular Formula	C12H9ClN4O2
Molecular Weight	276.68 g/mol
Synonyms	Ethyl 4-Chloro-[1,2,4]triazolo[4,3-a]quinoxaline-1-carboxylate; 4-Chloro-1-(ethoxycarbonyl)-[1,2,4]triazolo[4,3-a]quinoxaline; 1-Carbethoxy-4-chloro-[1,2,4]triazolo[4,3-a]quinoxaline; 4-Chloro-1H-[1,2,4]triazolo[4,3-a]quinoxaline-1-carboxylic acid ethyl ester; CTQCE; 1251017-01-2
EINECS	Contact for details

Quality Control

Our 4-Chloro-[1,2,4]Triazolo[4,3-A]Quinoxaline-1-Carboxylic Acid Ethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.