Description

1'-(tert-Butoxycarbonyl)-2-Oxospiro[Indoline-3,3'-Pyrrolidine]-4'-Carboxylic Acid is a sophisticated spirocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which serves as a versatile scaffold for constructing complex heterocyclic systems. It is primarily utilized by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, including kinase inhibitors and other biologically relevant small molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly those targeting protein kinases and other enzymes.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring complex spirocyclic frameworks.
• Academic & Industrial R&D: Serves as a valuable starting material for methodological chemistry research and the discovery of new chemical entities in industrial R&D labs.

Basic Information

Product Name	1'-(tert-Butoxycarbonyl)-2-Oxospiro[Indoline-3,3'-Pyrrolidine]-4'-Carboxylic Acid
CAS No.	1251011-21-8
Molecular Formula	C17H20N2O5
Molecular Weight	332.35 g/mol
Synonyms	Boc-Spiro[Indoline-3,3'-Pyrrolidine]-2-one-4'-carboxylic Acid; 1-[(2-Methyl-2-propanyl)oxycarbonyl]-2-oxospiro[3H-indole-3,3'-pyrrolidine]-4'-carboxylic Acid; 2-Oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylic Acid tert-Butyl Ester-4'-carboxylic Acid; tert-Butyl 2-oxo-4'-carboxyspiro[indoline-3,3'-pyrrolidine]-1'-carboxylate; (S)-1'-Boc-2-oxospiro[indoline-3,3'-pyrrolidine]-4'-carboxylic Acid (if chiral); (R)-1'-Boc-2-oxospiro[indoline-3,3'-pyrrolidine]-4'-carboxylic Acid (if chiral); 1'-Boc-2-oxospiro[indoline-3,3'-pyrrolidine]-4'-carboxylic Acid.
EINECS	Contact for details

Quality Control

Our 1'-(tert-Butoxycarbonyl)-2-Oxospiro[Indoline-3,3'-Pyrrolidine]-4'-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment where applicable, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.