Description

tert-Butyl 1,8-Dioxa-4,11-Diazaspiro[5.6]Dodecane-11-Carboxylate (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially those targeting the central nervous system (CNS) and other complex disease pathways.
• API Synthesis: Serves as a crucial building block in multi-step synthesis routes for constructing complex, spirocyclic-containing active pharmaceutical ingredients.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic benefits.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 1,8-Dioxa-4,11-Diazaspiro[5.6]Dodecane-11-Carboxylate (Saltdata: Free)
CAS No.	1251010-99-7
Molecular Formula	C14H26N2O4
Molecular Weight	286.37 g/mol
Synonyms	11-Boc-1,8-dioxa-4,11-diazaspiro[5.6]dodecane; tert-Butyl 1,8-dioxa-4,11-diazaspiro[5.6]dodecane-11-carboxylate; 1,8-Dioxa-4,11-diazaspiro[5.6]dodecane-11-carboxylic acid, 1,1-dimethylethyl ester; Boc-1,8-dioxa-4,11-diazaspiro[5.6]dodecane; Spirocyclic Boc-protected diamine ether
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 1,8-Dioxa-4,11-Diazaspiro[5.6]Dodecane-11-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Consider storing under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.