Description

1-Amino-6-Boc-6-Aza-Spiro[3.4]Octane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and protected amine structure. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel, complex molecules with potential therapeutic applications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing sophisticated active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Scaffold: Used to explore structure-activity relationships (SAR) due to its constrained spirocyclic framework and protected amine functionality.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog for the development of protease inhibitors and other bioactive peptides.
• Chemical Biology Probes: Utilized in the creation of tool compounds for target identification and validation in biological systems.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for advanced intermediates.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	1-Amino-6-Boc-6-Aza-Spiro[3.4]Octane
CAS No.	1251010-30-6
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	6-(tert-Butoxycarbonyl)-6-aza-1-aminospiro[3.4]octane; 1-Amino-6-[(tert-butoxy)carbonyl]-6-azaspiro[3.4]octane; tert-Butyl 1-amino-6-azaspiro[3.4]octane-6-carboxylate; 6-Aza-1-aminospiro[3.4]octane-6-carboxylic acid tert-butyl ester; 6-Boc-6-aza-1-aminospiro[3.4]octane; 1-Amino-6-Boc-6-azaspiro[3.4]octane; Boc-protected 6-aza-1-aminospiro[3.4]octane
EINECS	Contact for details

Quality Control

Our 1-Amino-6-Boc-6-Aza-Spiro[3.4]Octane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is supplied with each batch to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.