Description

6-Boc-1-Oxo-6-Aza-Spiro[3.4]Octane is a high-value, protected heterocyclic building block essential for modern organic synthesis. This compound matters as a key intermediate in the development of novel pharmaceuticals, particularly for constructing complex, three-dimensional molecular scaffolds found in active pharmaceutical ingredients (APIs). It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and biotechnology industries for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of spirocyclic compounds with potential therapeutic activity.
• Drug Discovery Scaffold: Used in medicinal chemistry to create novel chemical libraries for high-throughput screening against biological targets.
• API Synthesis: Serves as a key precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Proteolysis Targeting Chimera (PROTAC) Development: Utilized in constructing linkers and warhead components for targeted protein degradation therapeutics.
• Agrochemical Research: Employed in the development of new pesticides and herbicides with novel modes of action.
• Chemical Biology Probe Synthesis: Acts as a versatile intermediate for creating molecular tools to study biological pathways.

Basic Information

Product Name	6-Boc-1-Oxo-6-Aza-Spiro[3.4]Octane
CAS No.	1251010-17-9
Molecular Formula	C12H19NO3
Molecular Weight	225.28 g/mol
Synonyms	1-Oxo-6-aza-spiro[3.4]octane-6-carboxylic acid tert-butyl ester; tert-Butyl 1-oxo-6-azaspiro[3.4]octane-6-carboxylate; 6-(tert-Butoxycarbonyl)-6-aza-spiro[3.4]octan-1-one; 6-Boc-6-azaspiro[3.4]octan-1-one; 6-Azaspiro[3.4]octan-1-one, 6-[(1,1-dimethylethoxy)carbonyl]-; 6-Boc-6-azaspiro[3.4]octane-1-one; 6-Boc-1-oxo-6-azaspiro[3.4]octane
EINECS	Contact for details

Quality Control

Our 6-Boc-1-Oxo-6-Aza-Spiro[3.4]Octane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.