Description

1-Benzyl 9-tert-Butyl 1,4,9-Triazaspiro[5.5]Undecane-1,9-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the class of spirocyclic amines. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex molecules targeting various therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel drug candidates, particularly those exploring protease inhibitors or other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Acts as a core structural component in the design and synthesis of potential inhibitors for various protease enzymes.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring high-fidelity spirocyclic chemistry.

Basic Information

Item	Details
Product Name	1-Benzyl 9-tert-Butyl 1,4,9-Triazaspiro[5.5]Undecane-1,9-Dicarboxylate
CAS No.	1251008-98-6
Molecular Formula	C22H33N3O4
Molecular Weight	403.52 g/mol
Synonyms	1,4,9-Triazaspiro[5.5]undecane-1,9-dicarboxylic acid, 1-benzyl 9-(1,1-dimethylethyl) ester; 1-Benzyl 9-tert-butyl 1,4,9-triazaspiro[5.5]undecane-1,9-dicarboxylate; tert-Butyl 1-benzyl 1,4,9-triazaspiro[5.5]undecane-9-carboxylate-1-carboxylate; Spirocyclic Amine Ester Intermediate; BOC-Protected Triazaspiro Undecane Derivative
EINECS	Contact for details

Quality Control

Our 1-Benzyl 9-tert-Butyl 1,4,9-Triazaspiro[5.5]Undecane-1,9-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.