Description

8-Benzyl 11-tert-Butyl 2-Oxo-1,8,11-Triazaspiro[5.6]Dodecane-8,11-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic triaza scaffold. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas requiring constrained peptidomimetics and bioactive heterocycles.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Protease Inhibitor Scaffold: Used in the design and synthesis of potential inhibitors for various protease enzymes.
• Constrained Peptide Mimetics: Serves as a rigid core structure to mimic peptide secondary structures for enhanced metabolic stability and bioavailability.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies for oncology, virology, and CNS targets.
• Chemical Biology Probes: Utilized as a scaffold for developing tool compounds to study biological pathways and protein function.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	8-Benzyl 11-tert-Butyl 2-Oxo-1,8,11-Triazaspiro[5.6]Dodecane-8,11-Dicarboxylate
CAS No.	1251008-96-4
Molecular Formula	C22H31N3O5
Molecular Weight	417.50 g/mol
Synonyms	8-Benzyl 11-tert-butyl 2-oxo-1,8,11-triazaspiro[5.6]dodecane-8,11-dicarboxylate; 1,8,11-Triazaspiro[5.6]dodecane-8,11-dicarboxylic acid, 2-oxo-, 8-(phenylmethyl) 11-(1,1-dimethylethyl) ester; tert-Butyl 8-benzyl 2-oxo-1,8,11-triazaspiro[5.6]dodecane-8,11-dicarboxylate; 8-Benzyl 11-tert-butyl 2-oxo-1,8,11-triazaspiro[5.6]dodecane-8,11-dicarboxylate CAS 1251008-96-4; Spirocyclic Triaza Ester Intermediate; Benzyl tert-Butyl Triazaspirodecane Dicarboxylate
EINECS	Contact for details

Quality Control

Our production of 8-Benzyl 11-tert-Butyl 2-Oxo-1,8,11-Triazaspiro[5.6]Dodecane-8,11-Dicarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.