Description

2-Azaspiro[5.5]Undecan-2,9-Dicarboxylic Acid 2-tert-Butyl Ester is a high-value, protected spirocyclic amino acid derivative used as a critical building block in advanced organic synthesis. Its unique rigid, three-dimensional structure makes it an essential intermediate for constructing complex molecules with specific conformational properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, enhancing stability and biological activity.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study biological pathways and protein function.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides with novel modes of action.
• Material Science: Potential monomer or precursor for specialty polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Used in university and CRO laboratories for methodological development and exploring new chemical space.

Basic Information

Product Name	2-Azaspiro[5.5]Undecan-2,9-Dicarboxylic Acid 2-tert-Butyl Ester
CAS No.	1251008-89-5
Molecular Formula	C16H27NO4
Molecular Weight	297.39 g/mol
Synonyms	2-(tert-Butoxycarbonyl)-2-azaspiro[5.5]undecane-9-carboxylic acid; 2-Azaspiro[5.5]undecane-2,9-dicarboxylic acid, 2-(1,1-dimethylethyl) ester; 2-Boc-2-azaspiro[5.5]undecane-9-carboxylic acid; 9-Carboxy-2-Boc-2-azaspiro[5.5]undecane; 2-(tert-Butoxycarbonyl)-2-azaspiro[5.5]undecane-9-carboxylic Acid; tert-Butyl 9-carboxy-2-azaspiro[5.5]undecane-2-carboxylate; 2-Azaspiro[5.5]undecane-2,9-dicarboxylic acid mono-tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Azaspiro[5.5]Undecan-2,9-Dicarboxylic Acid 2-tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment. We support development projects with custom synthesis and analytical method development to meet specific research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.