Description

8-Amino-1-Azaspiro[4.5]Decan-2-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the production of active pharmaceutical ingredients, particularly those targeting neurological and psychiatric conditions.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.
• Academic Research: Utilized in university and institutional labs for synthetic methodology development and exploring new chemical spaces.

Basic Information

Product Name	8-Amino-1-Azaspiro[4.5]Decan-2-One
CAS No.	1251008-10-2
Molecular Formula	C9H16N2O
Molecular Weight	168.24 g/mol
Synonyms	8-Amino-1-azaspiro[4.5]decan-2-one; 1-Azaspiro[4.5]decan-2-one, 8-amino-; 8-Amino-1-azaspiro[4.5]decan-2-one; 8-Amino-2-oxo-1-azaspiro[4.5]decane; 2H-Azepin-2-one, hexahydro-8-amino-1H-1,4-diazepine-5-spiro-4'-piperidine; Spirocyclic lactam intermediate
EINECS	Contact for details

Quality Control

Our 8-Amino-1-Azaspiro[4.5]Decan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.