Description

tert-Butyl 8-Oxo-6-Oxa-2,9-Diazaspiro[4.5]Decane-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of innovative drug candidates, particularly in areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially those requiring complex spirocyclic architectures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic applications.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) targeting specific disease pathways.
• Proteolysis Targeting Chimera (PROTAC) Development: Its structural features make it a candidate for incorporation into bifunctional molecules designed for targeted protein degradation.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity intermediates.

Basic Information

Item	Details
Product Name	tert-Butyl 8-Oxo-6-Oxa-2,9-Diazaspiro[4.5]Decane-2-Carboxylate
CAS No.	1251007-91-6
Molecular Formula	C12H20N2O4
Molecular Weight	256.30 g/mol
Synonyms	2,9-Diazaspiro[4.5]decane-2-carboxylic acid, 8-oxo-6-oxa-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 8-oxo-6-oxa-2,9-diazaspiro[4.5]decane-2-carboxylate; tert-Butyl 8-oxo-6-oxa-2,9-diazaspiro[4.5]decane-2-carboxylate; 8-Oxo-6-oxa-2,9-diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester; Spirocyclic tert-butyl ester intermediate; Boc-protected diazaspirodecane derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 8-Oxo-6-Oxa-2,9-Diazaspiro[4.5]Decane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for advanced research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.