Description

1-Oxo-6-Oxa-9-Aza-Spiro[4.5]Decane-9-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, including potential candidates for central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules and novel APIs.
• Medicinal Chemistry Research: Used extensively in research and development for constructing spirocyclic scaffolds in drug discovery programs.
• Protease Inhibitor Synthesis: Acts as a building block for compounds targeting specific enzymatic pathways.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying biological mechanisms.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: A valuable reagent for universities and institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1-Oxo-6-Oxa-9-Aza-Spiro[4.5]Decane-9-Carboxylic Acid tert-Butyl Ester
CAS No.	1251000-29-9
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	tert-Butyl 1-oxo-6-oxa-9-azaspiro[4.5]decane-9-carboxylate; 9-Boc-1-oxo-6-oxa-9-azaspiro[4.5]decane; 6-Oxa-9-aza-spiro[4.5]decan-1-one, 9-(1,1-dimethylethoxy)carbonyl]-; 1-Oxo-6-oxa-9-azaspiro[4.5]decane-9-carboxylic acid 1,1-dimethylethyl ester; 9-N-Boc-1-oxo-6-oxa-9-azaspiro[4.5]decane; BOC-Protected 1-Oxo-6-Oxa-9-Aza-Spiro[4.5]Decane
EINECS	Contact for details

Quality Control

Our 1-Oxo-6-Oxa-9-Aza-Spiro[4.5]Decane-9-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.