Description

2-(3,5-Dimethylphenyl)-2,2-Difluoroacetic Acid is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoroacetate moiety, which is crucial for introducing fluorine atoms into complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Advanced Polymer Modification: Employed to introduce fluorine-containing functional groups into polymer backbones, altering surface properties and chemical resistance.
• Organic Electronics: Acts as a building block for electron-deficient materials used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and constructing complex, fluorinated heterocycles in academic and industrial labs.

Basic Information

Product Name	2-(3,5-Dimethylphenyl)-2,2-Difluoroacetic Acid
CAS No.	1250511-94-4
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2,2-Difluoro-2-(3,5-dimethylphenyl)acetic Acid; α,α-Difluoro-3,5-dimethylphenylacetic Acid; 3,5-Dimethyl-α,α-difluorobenzeneacetic Acid; (3,5-Dimethylphenyl)difluoroacetic Acid; 2-(3,5-Dimethylphenyl)-2,2-difluoroethanoic Acid; DFMPAA; DFDMPA
EINECS	Contact for details

Quality Control

Our 2-(3,5-Dimethylphenyl)-2,2-Difluoroacetic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.