Description

4-Bromo-3-Fluoro-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the fluorine and nitro groups for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Acts as a starting material for creating sophisticated ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags and molecular probes for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Item	Details
Product Name	4-Bromo-3-Fluoro-5-Nitrobenzoic Acid
CAS No.	1249531-65-4
Molecular Formula	C7H3BrFNO4
Molecular Weight	264.01 g/mol
Synonyms	4-Bromo-3-fluoro-5-nitrobenzoic acid; 3-Fluoro-5-nitro-4-bromobenzoic acid; Benzoic acid, 4-bromo-3-fluoro-5-nitro-; 1249531-65-4; 4-Br-3-F-5-NO2-BA; 4-Bromo-3-fluoro-5-nitro-benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Fluoro-5-Nitrobenzoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.