Description

8-(Methylsulfonyl)-8-Azabicyclo[3.2.1]Octan-3-Amine CAS NO 1249024-78-9 is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel therapeutic agents, particularly those targeting the central nervous system.
• Drug Discovery & Development: Serves as a versatile scaffold in medicinal chemistry for creating libraries of compounds to screen for biological activity.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the final or penultimate steps of manufacturing specific, high-value APIs.
• Biochemical Research: Employed as a reference standard or a tool compound in pharmacological and metabolic studies.
• Contract Manufacturing (CMO/CDMO): Supplied to outsourcing partners who require reliable, high-quality building blocks for client projects.

Basic Information

Product Name	8-(Methylsulfonyl)-8-Azabicyclo[3.2.1]Octan-3-Amine
CAS No.	1249024-78-9
Molecular Formula	C8H16N2O2S
Molecular Weight	204.29 g/mol
Synonyms	8-Azabicyclo[3.2.1]octan-3-amine, 8-(methylsulfonyl)-; 8-Methanesulfonyl-8-azabicyclo[3.2.1]octan-3-amine; 3-Amino-8-(methylsulfonyl)-8-azabicyclo[3.2.1]octane; 8-Mesyl-8-azabicyclo[3.2.1]octan-3-amine; Nortropin-3-amine, 8-(methylsulfonyl)-; Tropane-3-amine, 8-(methylsulfonyl)- (derivative); 1249024-78-9; 8-(Methylsulfonyl)-3-aminotropane
EINECS	Contact for details

Quality Control

Every batch of 8-(Methylsulfonyl)-8-Azabicyclo[3.2.1]Octan-3-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.