Description

8-Bromo-1,2-Dihydro-2-Oxoquinoline-4-Carboxylic Acid is a high-value brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated oxoquinoline structure makes it an essential building block for constructing complex molecules with targeted biological activity. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or possessing anti-infective properties.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactive quinoline scaffold.
• Material Science: Serves as a building block for creating organic ligands in metal-organic frameworks (MOFs) or functional polymers.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinoline moiety into more complex structures.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and methodological studies.

Basic Information

Product Name	8-Bromo-1,2-Dihydro-2-Oxoquinoline-4-Carboxylic Acid
CAS No.	1248595-74-5
Molecular Formula	C₁₀H₆BrNO₃
Molecular Weight	268.07 g/mol
Synonyms	8-Bromocarbostyril-4-carboxylic Acid; 8-Bromo-4-carboxy-2-quinolone; 8-Bromo-1,2-dihydro-2-oxo-4-quinolinecarboxylic Acid; 8-Bromo-2-oxo-1,2-dihydroquinoline-4-carboxylic Acid; 4-Quinolinecarboxylic acid, 8-bromo-1,2-dihydro-2-oxo-; 8-Bromo-4-CQA
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-1,2-Dihydro-2-Oxoquinoline-4-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and we support custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive and should be handled accordingly. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.