Description

n-Ethyl-2,3-Difluoro-6-Nitroaniline is a high-value, multi-functional aromatic amine building block characterized by its unique substitution pattern of ethyl, nitro, and fluorine groups. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts specific electronic and steric properties. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides and pesticides with enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials due to its fluorine-containing aromatic core.
• Dye & Pigment Intermediate: Employed in the manufacture of specialized dyes and pigments where the nitro and amine functionalities are crucial for color development.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for engineering polymers with specific thermal or chemical resistance.
• Organic Synthesis Reagent: A versatile reagent in academic and industrial research for introducing the difluoro-nitroaniline moiety into more complex molecules.

Basic Information

Product Name	n-Ethyl-2,3-Difluoro-6-Nitroaniline
CAS No.	1248209-18-8
Molecular Formula	C8H8F2N2O2
Molecular Weight	202.16 g/mol
Synonyms	2,3-Difluoro-6-nitro-N-ethylaniline; N-Ethyl-2,3-difluoro-6-nitrobenzenamine; 1-Ethylamino-2,3-difluoro-4-nitrobenzene; 6-Nitro-2,3-difluoro-N-ethylaniline; Benzenamine, 2,3-difluoro-6-nitro-N-ethyl-; 1248209-18-8; N-Ethyl-2,3-difluoro-6-nitroaniline
EINECS	Contact for details

Quality Control

Our n-Ethyl-2,3-Difluoro-6-Nitroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.