Description

Difluoro-(1-Methyl-1H-Pyrazol-4-Yl)-Acetic Acid is a high-value fluorinated pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in introducing a difluoroacetic acid moiety onto a heterocyclic scaffold, enabling precise modulation of molecular properties for target applications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other enzyme modulators.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atoms can improve lipophilicity and biological activity.
• Ligand Synthesis: Serves as a precursor for creating complex ligands in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes for studying biological processes and protein interactions.
• Advanced Material Development: Incorporated into specialty polymers and functional materials to impart specific chemical and physical properties.

Basic Information

Product Name	Difluoro-(1-Methyl-1H-Pyrazol-4-Yl)-Acetic Acid
CAS No.	1248011-19-9
Molecular Formula	C7H8F2N2O2
Molecular Weight	190.15 g/mol
Synonyms	2,2-Difluoro-2-(1-methyl-1H-pyrazol-4-yl)acetic acid; 2-(1-Methyl-1H-pyrazol-4-yl)-2,2-difluoroacetic acid; (1-Methyl-1H-pyrazol-4-yl)difluoroacetic acid; 4-(Difluorocarboxymethyl)-1-methylpyrazole; DFMPA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of Difluoro-(1-Methyl-1H-Pyrazol-4-Yl)-Acetic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.