Description

1-(1,3-Thiazol-2-Yl)-1H-Pyrazole-4-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring fused pyrazole and thiazole rings, makes it a critical intermediate for the development of novel active compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create new molecules with targeted biological functions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology & Medicinal Chemistry: Acts as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis or metal-organic frameworks due to its carboxylic acid and nitrogen-containing heterocycles.
• Material Science Research: Investigated as a monomer or functional component for creating novel polymers and advanced organic materials.

Basic Information

Product Name	1-(1,3-Thiazol-2-Yl)-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1247644-96-7
Molecular Formula	C7H5N3O2S
Molecular Weight	195.20 g/mol
Synonyms	1-(Thiazol-2-yl)-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 1-(2-thiazolyl)-; 2-(4-Carboxy-1H-pyrazol-1-yl)thiazole; 1-(1,3-Thiazol-2-yl)-1H-pyrazole-4-carboxylic acid; 1247644-96-7; TZPCA; Thiazolylpyrazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(1,3-Thiazol-2-Yl)-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is stable under these conditions but should be kept away from strong acids and organic solvents as indicated by its chemical properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.