Description

(2R,5R)-1,6-Diphenylhexane-2,5-Diamine Dihydrochloride is a high-purity chiral diamine salt, a critical building block in advanced organic synthesis. Its value lies in its stereochemical purity, which is essential for producing enantiomerically pure compounds with specific biological or material properties. This product is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in asymmetric catalysis, chiral ligand synthesis, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst Ligand: Serves as a backbone for constructing sophisticated chiral ligands used in enantioselective hydrogenation and C-C bond-forming reactions.
• Chiral Resolution Agent: Employed in the separation of racemic mixtures due to its defined stereochemistry.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and constrained scaffolds for drug discovery.
• Material Science: A monomer for developing chiral polymers and advanced functional materials with specific optical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(2R,5R)-1,6-Diphenylhexane-2,5-Diamine Dihydrochloride
CAS No.	1247119-31-8
Molecular Formula	C18H26N2 • 2HCl
Molecular Weight	347.33 g/mol (Free base: 270.41 g/mol)
Synonyms	(2R,5R)-1,6-Diphenyl-2,5-hexanediamine Dihydrochloride; (2R,5R)-DPHDA•2HCl; (2R,5R)-1,6-Diphenylhexane-2,5-diamine Hydrochloride; (2R,5R)-Hexane-2,5-diamine, 1,6-diphenyl-, dihydrochloride; (2R,5R)-1,6-Diphenylhexane-2,5-diyldiamine Dihydrochloride; (2R,5R)-2,5-Diamino-1,6-diphenylhexane Dihydrochloride; (R,R)-1,6-Diphenylhexane-2,5-diamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our (2R,5R)-1,6-Diphenylhexane-2,5-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.