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1,3:4,6-Di-o-Benzylidene-2,5-Dideoxy-2,5-Imino-L-Iditol (Mixture Of Diastereomers) CAS NO 1246812-42-9


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CAS No.:1246812-42-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,3:4,6-Di-o-Benzylidene-2,5-Dideoxy-2,5-Imino-L-Iditol (Mixture Of Diastereomers) is a specialized chiral iminosugar derivative that serves as a critical synthetic intermediate and a valuable scaffold in medicinal chemistry research. This compound matters for its role as a key building block in the development of glycosidase inhibitors and other bioactive molecules targeting carbohydrate-processing enzymes. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for the synthesis of potential therapeutics for metabolic disorders, viral infections, and cancer.

Application

  • Pharmaceutical Intermediate: Key chiral building block for the synthesis of potent glycosidase and glycosyltransferase inhibitors.
  • Medicinal Chemistry Research: Scaffold for developing novel drug candidates targeting diabetes, Gaucher's disease, and influenza.
  • Biochemical Tool Compound: Used in enzymatic studies to investigate the mechanism and inhibition of carbohydrate-active enzymes.
  • Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective organic synthesis.
  • Academic Research: Fundamental studies in carbohydrate mimetics and chemical biology.
  • Process Development: Serves as a reference standard and starting material in the scale-up and optimization of synthetic routes for complex iminosugars.

Basic Information

Product Name 1,3:4,6-Di-o-Benzylidene-2,5-Dideoxy-2,5-Imino-L-Iditol (Mixture Of Diastereomers)
CAS No. 1246812-42-9
Molecular Formula C20H21NO4
Molecular Weight 339.39 g/mol
Synonyms 1,3:4,6-Di-O-benzylidene-2,5-dideoxy-2,5-imino-L-iditol; 2,5-Dideoxy-2,5-imino-1,3:4,6-di-O-benzylidene-L-iditol; L-Iditol, 2,5-dideoxy-2,5-imino-1,3:4,6-di-O-(phenylmethylene)-, (2R,3R,4R,5R)-rel-; Di-benzylidene protected DNI derivative; Iminosugar benzylidene acetal; Glycosidase inhibitor intermediate; 1,3:4,6-Di-O-benzylidene-DNI
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Quality Control

Our 1,3:4,6-Di-o-Benzylidene-2,5-Dideoxy-2,5-Imino-L-Iditol is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and diastereomeric ratio assessment, NMR, and MS for structural confirmation. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all relevant specifications to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Diastereomeric Ratio (HPLC) Specified on COA
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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