Description

1-(2,2-Difluoro-Ethyl)-3-Methoxy-4-Nitro-1H-Pyrazole is a specialized fluorinated pyrazole derivative, a high-value intermediate critical for advanced chemical synthesis. Its molecular structure, featuring difluoroethyl and nitro-methoxy substituents, makes it a key building block for developing novel active ingredients. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds, leveraging its reactive nitro and methoxy groups for further functionalization.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique electronic or surface properties.
• Life Science Reagent: Utilized in biochemical research as a tool compound or a probe for studying enzyme inhibition and other biological pathways.

Basic Information

Product Name	1-(2,2-Difluoro-Ethyl)-3-Methoxy-4-Nitro-1H-Pyrazole
CAS No.	1245771-68-9
Molecular Formula	C6H7F2N3O3
Molecular Weight	207.14 g/mol
Synonyms	1-(2,2-Difluoroethyl)-3-methoxy-4-nitro-1H-pyrazole; 3-Methoxy-4-nitro-1-(2,2-difluoroethyl)-1H-pyrazole; 4-Nitro-3-methoxy-1-(2,2-difluoroethyl)pyrazole; 1H-Pyrazole, 1-(2,2-difluoroethyl)-3-methoxy-4-nitro-; Difluoroethyl Methoxy Nitropyrazole; DFEMNP
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is manufactured under controlled conditions and analyzed to meet precise specifications for identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing results from HPLC, NMR, and other analytical methods are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.