Description

(3S)-3-Amino-1,2,3,4-Tetrahydroquinolin-1-Ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its defined stereochemistry and functionalized tetrahydroquinoline scaffold make it a valuable precursor in modern synthetic chemistry, particularly for the development of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop novel compounds with specific biological activity. The CAS number for this material is 1245647-56-6.

Application

This advanced intermediate is utilized in a variety of research and industrial synthesis applications, including:

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Catalyst and Ligand Development: Serves as a precursor for creating novel chiral catalysts and ligands used in asymmetric synthesis.
• Academic and R&D: A valuable compound for medicinal chemistry research, library synthesis, and exploring new chemical entities in university and corporate laboratories.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	(3S)-3-Amino-1,2,3,4-Tetrahydroquinolin-1-Ol Hydrochloride
CAS No.	1245647-56-6
Molecular Formula	C9H13ClN2O
Molecular Weight	200.67 g/mol
Synonyms	(3S)-1-Hydroxy-1,2,3,4-tetrahydroquinolin-3-amine hydrochloride; (3S)-3-Amino-3,4-dihydro-1H-quinolin-1-ol hydrochloride; 1H-Quinolin-1-ol, 3-amino-3,4-dihydro-, hydrochloride, (3S)-; (S)-3-Amino-1,2,3,4-tetrahydroquinolin-1-ol HCl; (S)-3-Aminotetrahydroquinolin-1-ol hydrochloride; 1245647-56-6; (3S)-3-Amino-1,2,3,4-tetrahydroquinolin-1-ol HCl salt
EINECS	Contact for details

Quality Control

Our (3S)-3-Amino-1,2,3,4-Tetrahydroquinolin-1-Ol Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.