Description

(1-Methylcyclobutyl)Methanamine Hydrochloride is a high-purity organic amine salt with the CAS number 1245647-53-3, serving as a critical building block in advanced organic synthesis. Its value lies in its unique sterically hindered amine structure, which is essential for modulating the physicochemical properties and biological activity of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral or sterically hindered synthon for the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where its amine moiety can enhance efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and specialty polymers requiring tailored amine functionalities.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for contract research organizations (CROs) serving the life sciences sector.

Basic Information

Product Name	(1-Methylcyclobutyl)Methanamine Hydrochloride
CAS No.	1245647-53-3
Molecular Formula	C7H16ClN
Molecular Weight	149.66 g/mol
Synonyms	1-(Aminomethyl)-1-methylcyclobutane hydrochloride; (1-Methylcyclobutyl)methylamine hydrochloride; 1-Methylcyclobutane-1-methanamine hydrochloride; (1-Methylcyclobutyl)methanamine HCl; Cyclobutane, 1-(aminomethyl)-1-methyl-, hydrochloride; 1-Methyl-1-(aminomethyl)cyclobutane hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (1-Methylcyclobutyl)Methanamine Hydrochloride is manufactured under a strict quality management system. We perform comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.