Description

2-Amino-2-(2,3-Difluorophenyl)Ethan-1-Ol Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its chiral amino alcohol structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• API Synthesis: Serves as a crucial precursor in multi-step synthetic routes for constructing complex molecular architectures found in proprietary APIs.
• Asymmetric Catalysis Research: Used as a ligand precursor or a chiral auxiliary in academic and industrial research focused on asymmetric synthesis methodologies.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to explore and optimize the biological activity of lead compounds.

Basic Information

Product Name	2-Amino-2-(2,3-Difluorophenyl)Ethan-1-Ol Hydrochloride
CAS No.	1245622-86-9
Molecular Formula	C8H8F2NO•HCl
Molecular Weight	209.61 g/mol (Free base: 173.15 g/mol)
Synonyms	2-Amino-2-(2,3-difluorophenyl)ethanol hydrochloride; (R/S)-2-Amino-2-(2,3-difluorophenyl)ethan-1-ol hydrochloride; 1-(2,3-Difluorophenyl)-2-aminoethanol hydrochloride; 2,3-Difluoro-β-amino-phenethyl alcohol hydrochloride; α-Amino-2,3-difluorobenzeneethanol hydrochloride; Amino alcohol difluorophenyl hydrochloride; 1245622-86-9
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(2,3-Difluorophenyl)Ethan-1-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and compliance with your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.