Description

8-Bromo-6-iodoquinoline is a high-purity halogenated quinoline derivative, a crucial building block in advanced organic synthesis. Its unique bifunctional halogenated structure makes it an indispensable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially in developing kinase inhibitors, antimicrobial agents, and other biologically active quinoline-based molecules.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of organic electronic materials, such as OLEDs and conductive polymers, due to its electron-deficient aromatic system.
• Ligand Synthesis: Employed for preparing novel chelating ligands in catalysis and coordination chemistry, where the halogen atoms provide sites for further functionalization.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig) to introduce complex substituents onto the quinoline core.
• Chemical Biology: Utilized as a molecular probe or tag in bioconjugation and labeling studies.

Basic Information

Product Name	8-Bromo-6-iodoquinoline
CAS No.	1245563-17-0
Molecular Formula	C9H5BrIN
Molecular Weight	333.95 g/mol
Synonyms	6-Iodo-8-bromoquinoline; Quinoline, 8-bromo-6-iodo-; 8-Bromo-6-iodo-quinoline; 1245563-17-0; 8-Br-6-I-quinoline
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-6-iodoquinoline is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is supplied with each shipment to guarantee reproducible results and supply chain integrity for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.