Description

2-Isopropoxy-4-(Trifluoromethyl)Phenol is a specialized phenolic compound featuring a trifluoromethyl group and an isopropoxy substituent. This unique structure makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring the trifluoromethyl moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the phenol and trifluoromethyl groups contribute to biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for functional dyes and electronic chemicals used in display technologies and organic light-emitting diodes.
• Polymer Modification: Acts as a monomer or additive to introduce specific functional groups into polymer chains, altering material properties.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a ligand precursor in catalytic systems for fine chemical manufacturing.

Basic Information

Product Name	2-Isopropoxy-4-(Trifluoromethyl)Phenol
CAS No.	1243353-40-3
Molecular Formula	C10H11F3O2
Molecular Weight	220.19 g/mol
Synonyms	4-(Trifluoromethyl)-2-isopropoxyphenol; 2-Isopropoxy-α,α,α-trifluoro-p-cresol; 1-Hydroxy-2-isopropoxy-4-(trifluoromethyl)benzene; Phenol, 2-isopropoxy-4-(trifluoromethyl)-; 2-(1-Methylethoxy)-4-(trifluoromethyl)phenol
EINECS	Contact for details

Quality Control

Our production of 2-Isopropoxy-4-(Trifluoromethyl)Phenol adheres to stringent GMP and ISO 9001 guidelines to ensure batch-to-batch consistency and high purity. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.