Description

3-Chloro-2-Fluoro-5-(Chlorosulfonyl)Benzoic Acid is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. Its unique structure, featuring both a reactive chlorosulfonyl group and a carboxylic acid moiety on a halogenated benzene ring, makes it an indispensable intermediate for creating complex molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the chlorosulfonyl group enables the introduction of sulfonamide or sulfonate functionalities.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, liquid crystals, and advanced materials with specific thermal or optical properties.
• Organic Synthesis & Research: A versatile reagent for constructing complex heterocycles and for introducing the benzoic acid and sulfonyl chloride motifs in multi-step synthetic routes.
• Dye & Pigment Manufacturing: Intermediate in the production of specialized dyes and pigments, leveraging its halogenated and functionalized aromatic core.

Basic Information

Product Name	3-Chloro-2-Fluoro-5-(Chlorosulfonyl)Benzoic Acid
CAS No.	1242339-12-3
Molecular Formula	C7H3Cl2FO4S
Molecular Weight	273.07 g/mol
Synonyms	5-(Chlorosulfonyl)-3-chloro-2-fluorobenzoic acid; Benzoic acid, 3-chloro-2-fluoro-5-(chlorosulfonyl)-; 3-Chloro-2-fluoro-5-sulfonylchloride benzoic acid; 2-Fluoro-3-chloro-5-(chlorosulfonyl)benzoic acid; 3-Chloro-2-fluorobenzoic-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Fluoro-5-(Chlorosulfonyl)Benzoic Acid is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards through rigorous analytical controls, including HPLC, NMR, and titration methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.