Description

4-Bromo-3-Fluoro-5-(Chlorosulfonyl)Benzoic Acid is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. Its unique structure, featuring bromo, fluoro, and chlorosulfonyl substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for functional polymers, liquid crystals, and advanced organic electronic materials due to its reactive sulfonyl chloride and carboxylic acid groups.
• Chemical Research & Development: An invaluable tool in medicinal and process chemistry for structure-activity relationship (SAR) studies and the introduction of specific functional groups.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of specialized dyes and pigments, where the sulfonyl group can be further modified.

Basic Information

Product Name	4-Bromo-3-Fluoro-5-(Chlorosulfonyl)Benzoic Acid
CAS No.	1242338-82-4
Molecular Formula	C7H3BrClFO4S
Molecular Weight	317.52 g/mol
Synonyms	Benzoic acid, 4-bromo-3-fluoro-5-(chlorosulfonyl)-; 5-(Chlorosulfonyl)-4-bromo-3-fluorobenzoic acid; 4-Bromo-3-fluoro-5-sulfonylchloride-benzoic acid; 3-Fluoro-4-bromo-5-(chlorosulfonyl)benzoic acid; 4-Bromo-3-fluoro-5-chlorosulfonylbenzoic acid; CAS 1242338-82-4
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Fluoro-5-(Chlorosulfonyl)Benzoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.