Description

4-Bromo-6,8-Difluoroquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex pharmacologically active molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial R&D departments engaged in medicinal chemistry, where it facilitates the creation of novel quinolone-based drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antibacterial and antiviral agents, leveraging the bioactive quinoline scaffold.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the difluoro and bromo substituents impart unique biological activity.
• Material Science: Serves as a building block for creating advanced organic electronic materials and functional dyes.
• Academic & Contract Research: Essential for method development and exploratory synthesis in university and CRO laboratories focused on heterocyclic chemistry.
• Fluorinated Compound Library Synthesis: A valuable reagent for constructing diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	4-Bromo-6,8-Difluoroquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-74-7
Molecular Formula	C₁₂H₈BrF₂NO₂
Molecular Weight	316.10 g/mol
Synonyms	Ethyl 4-Bromo-6,8-difluoroquinoline-3-carboxylate; 4-Bromo-6,8-difluoro-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 4-bromo-6,8-difluoro-, ethyl ester; 1242260-74-7; 4-Bromo-6,8-difluoroquinoline-3-carboxylic acid ethyl ester; Ethyl 4-bromo-6,8-difluorochinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Bromo-6,8-Difluoroquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.