Description

7-Bromo-4-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its complex halogenated and esterified structure makes it a valuable building block for constructing sophisticated molecular architectures, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the life sciences sector who require reliable, high-quality intermediates to drive innovation in drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting infectious diseases, oncology, and central nervous system disorders.
• Agrochemical Research: Used in the development of new-generation fungicides, herbicides, and pesticides, leveraging its quinoline core for bioactivity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for generating diverse heterocyclic compound libraries for screening.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing complex quinoline-based dyes and fluorescent markers.

Basic Information

Product Name	7-Bromo-4-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-50-9
Molecular Formula	C₁₄H₁₁BrClNO₂
Molecular Weight	344.60 g/mol
Synonyms	Ethyl 7-Bromo-4-chloro-8-methylquinoline-3-carboxylate; 7-Bromo-4-chloro-8-methylquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 7-bromo-4-chloro-8-methyl-, ethyl ester; 1242260-50-9; Ethyl 7-bromo-4-chloro-8-methyl-3-quinolinecarboxylate; 8-Methyl-7-bromo-4-chloro-quinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 7-Bromo-4-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) that detail specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.