Description

4,8-Dichloro-5-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based drug candidates, particularly in therapeutic areas like oncology and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, dyes, or functional organic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring structure-activity relationships (SAR).
• Process Chemistry Development: Used by chemical engineers to scale up and optimize synthetic routes for commercial production of target molecules.

Basic Information

Product Name	4,8-Dichloro-5-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-49-6
Molecular Formula	C₁₃H₁₁Cl₂NO₃
Molecular Weight	300.14 g/mol
Synonyms	Ethyl 4,8-dichloro-5-methoxyquinoline-3-carboxylate; 4,8-Dichloro-5-methoxyquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4,8-dichloro-5-methoxy-, ethyl ester; 1242260-49-6; Ethyl 4,8-dichloro-5-methoxy-3-quinolinecarboxylate; 5-Methoxy-4,8-dichloroquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 4,8-Dichloro-5-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.