Description

4-Bromo-6-Fluoroquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its unique halogenated quinoline scaffold, which serves as a critical precursor in the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of complex drug candidates, particularly in the areas of antimicrobial and anticancer research.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel quinolone and quinoline-based APIs, especially those targeting bacterial infections and specific cancer pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for creating specialized organic ligands and functional molecules used in catalysis and advanced materials.
• Academic & R&D: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and corporate laboratories.
• Fluorescent Probe Development: Potential use in creating fluorophore derivatives for biochemical sensing and imaging applications.

Basic Information

Product Name	4-Bromo-6-Fluoroquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-48-5
Molecular Formula	C₁₂H₉BrFNO₂
Molecular Weight	298.11 g/mol
Synonyms	Ethyl 4-Bromo-6-fluoroquinoline-3-carboxylate; 4-Bromo-6-fluoro-3-quinolinecarboxylic acid ethyl ester; 6-Fluoro-4-bromoquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4-bromo-6-fluoro-, ethyl ester; 1242260-48-5; 4-Bromo-6-fluoroquinoline-3-carboxylate ethyl ester; Ethyl 4-bromo-6-fluoro-3-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Fluoroquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the rigorous standards expected in pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.