Description

4-Bromo-5-Chloro-8-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional quinoline derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique halogenated and methoxylated structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and pesticides, leveraging its halogenated quinoline core.
• Material Science Precursor: Serves as a starting material for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis Reagent: Employed in cross-coupling reactions, functional group transformations, and as a scaffold for combinatorial chemistry libraries.
• Academic & R&D: A valuable tool for medicinal chemistry research, process development, and studying structure-activity relationships (SAR).

Basic Information

Product Name	4-Bromo-5-Chloro-8-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-39-4
Molecular Formula	C₁₃H₁₁BrClNO₃
Molecular Weight	344.59 g/mol
Synonyms	Ethyl 4-Bromo-5-Chloro-8-Methoxyquinoline-3-Carboxylate; 8-Methoxy-4-bromo-5-chloroquinoline-3-carboxylic Acid Ethyl Ester; 4-Bromo-5-chloro-8-methoxy-3-quinolinecarboxylic Acid Ethyl Ester; Quinoline-3-carboxylic Acid, 4-Bromo-5-Chloro-8-Methoxy-, Ethyl Ester; 1242260-39-4; Ethyl 4-Bromo-5-Chloro-8-Methoxy-3-Quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-8-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.