Description

4-Amino-5-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable quinoline derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure makes it an essential intermediate for the development of novel pharmaceutical compounds, particularly in medicinal chemistry research. This product is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and anti-infective pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Agrochemical Synthesis: Serves as a building block for developing novel fungicides and herbicides with quinoline-based activity.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and reaction mechanisms.
• Chemical Reference Standard: Can be supplied as a certified reference material for analytical method development and quality control.

Basic Information

Item	Details
Product Name	4-Amino-5-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1242260-30-5
Molecular Formula	C₁₃H₁₃ClN₂O₂
Molecular Weight	264.71 g/mol
Synonyms	Ethyl 4-Amino-5-chloro-8-methylquinoline-3-carboxylate; 4-Amino-5-chloro-8-methyl-3-quinolinecarboxylic acid ethyl ester; 5-Chloro-8-methyl-4-aminoquinoline-3-carboxylic acid ethyl ester; AQCE; 1242260-30-5; UNII-8V4A4N6W5P; 8V4A4N6W5P; SCHEMBL21824027; DTXSID90654266
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.