Description

4-Bromo-8-Methylquinoline-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound matters for its crucial role in the synthesis of complex molecules, particularly in medicinal chemistry for drug discovery and development. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for catalysis, and specialty polymers.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyclization reactions to construct more complex heterocyclic systems.
• Academic & R&D: Employed in university and industrial research laboratories for methodological studies and exploring new chemical spaces.
• Ligand Synthesis: The nitrile and bromo functional groups make it a useful starting material for synthesizing chelating ligands in coordination chemistry.

Basic Information

Product Name	4-Bromo-8-Methylquinoline-3-Carbonitrile
CAS No.	1242260-28-1
Molecular Formula	C11H7BrN2
Molecular Weight	247.09 g/mol
Synonyms	4-Bromo-8-methylquinoline-3-carbonitrile; 8-Methyl-4-bromoquinoline-3-carbonitrile; 3-Cyano-4-bromo-8-methylquinoline; Quinoline-3-carbonitrile, 4-bromo-8-methyl-; 1242260-28-1; 4-Bromo-8-methyl-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-8-Methylquinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.